Skip to content
Open Imaging Index
MRI Brain

SUDMEX TMS (ds003037)

SUDMEX TMS: The Mexican dataset of a repetitive transcranial magnetic stimulation clinical trial on cocaine use disorder patients

Longitudinal brain MRI of people with cocaine use disorder, collected in a randomized sham-controlled trial of repetitive transcranial magnetic stimulation (rTMS) with follow-up up to 12 months. 53 patients from Mexico City with structural, diffusion and resting-state scans, CC0.

Go to dataset Edit Report

Overview

SUDMEX TMS holds the brain MRI of a double-blind, placebo-controlled randomized trial at the National Institute of Psychiatry Ramón de la Fuente Muñiz in Mexico City (NCT02986438). The trial tested 5 Hz rTMS over the left dorsolateral prefrontal cortex as an add-on to usual treatment for cocaine use disorder (CUD), followed by an open-label maintenance phase. The images were released on OpenNeuro as ds003037 in 2020 under a CC0 waiver; the data descriptor appeared in Scientific Data in 2024 and describes snapshot 2.1.0. It is a sister dataset of SUDMEX CONN, scanned on the same scanner.

Composition

Snapshot 2.1.0 contains 53 patients and 156 MRI sessions. Every patient has a baseline session (T0). Follow-up sessions were planned after the two-week blinded phase (T1), at 3, 6 and 12 months (T2 to T4), and two weeks after T1 for sham patients who then chose open-label rTMS (T14). The participants table covers 50 patients with age (18 to 48), sex, arm (23 sham, 27 active), years of education and an exclusion flag that marks 6 of them. Clinical scales and cognitive tests for each study phase are published separately on Zenodo.

Acquisition

Scanning ran from 2017 to 2019 on one Philips Ingenia 3T with a 32-channel head coil, about 50 minutes per session. Each session had a 10-minute eyes-open resting-state EPI (TR 2 s, 300 volumes), a mostly 1 mm isotropic 3D T1-weighted scan and a multishell HARDI diffusion scan (b = 1000 and 2500 s/mm², b = 3000 for the first 4 patients), each EPI series with a reverse phase-encoded field map. Images are BIDS NIfTI, defaced with pydeface.

Annotations

There are no image annotations. CUD was diagnosed with the MINI-Plus interview. The paper reports MRIQC and EDDY QC metrics per session.

Known limitations

  • The paper reports 54 patients (30 active, 24 sham) in the text and 53 (30 active, 23 sham) in Table 1; the release has 53 subject folders, and 3 of them have no participants.tsv row.
  • Attrition is high: 45 patients have a T1 session, 15 a T3 and 7 a T4.
  • 2 patients have a session labelled t5 that neither the README nor the paper describes.
  • Some patients moved a lot during scanning; the authors recommend artifact correction.

Cohort

Aggregate numbers from the sources below. Bars are relative to the 53 subjects.

Sex

  • Female 7 14%
  • Male 43 86%

Covers 50 of 53 subjects.

sex in participants.tsv of ds003037 snapshot 2.1.0 (CC0), 50 rows; sex and age columns

Contrast / sequence

Groups can overlap

  • T1-weighted 53 100%
  • BOLD fMRI 53 100%
  • Diffusion-weighted 52 98%

anat, func, dwi in File tree of ds003037 snapshot 2.1.0 (CC0), sessions with a T1w, dwi or bold NIfTI file

Scanner vendor

  • Philips 53 100%

Magnetic resonance imaging acquisition in Angeles-Valdez et al. 2024, The Mexican dataset of a repetitive transcranial magnetic stimulation clinical trial on cocaine use disorder patients: SUDMEX TMS, Scientific Data

Age

mean 34.8 ± 7.7, median 35, range 18 to 48

0
10
20
22
10-1920-2930-3940-49

age in participants.tsv of ds003037 snapshot 2.1.0 (CC0), 50 rows; sex and age columns

Condition

Groups can overlap

  • Cocaine use disorder 53 100%

Methods, Participants in Angeles-Valdez et al. 2024, The Mexican dataset of a repetitive transcranial magnetic stimulation clinical trial on cocaine use disorder patients: SUDMEX TMS, Scientific Data

Field strength

  • 3 T 53 100%

Magnetic resonance imaging acquisition in Angeles-Valdez et al. 2024, The Mexican dataset of a repetitive transcranial magnetic stimulation clinical trial on cocaine use disorder patients: SUDMEX TMS, Scientific Data

Age by sex

Reported cross table. Missing cells were not published (fewer than 10 or not reported).

Female Male
  • n/a
    40-49
    11
  • n/a
    30-39
    20
  • n/a
    20-29
    10

sex and age in participants.tsv of ds003037 snapshot 2.1.0 (CC0), 50 rows; sex and age columns

Contrast combinations

How many subjects have exactly each set of contrasts.

T1wdwiboldSubjects with exactly this set
52
1

From File tree of ds003037 snapshot 2.1.0 (CC0), sessions with a T1w, dwi or bold NIfTI file

License and access

Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer

Access
Open download

Download without an account

Access page

Creative Commons Zero 1.0 Universal

Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.

dataset_description.json of snapshot 2.1.0 states "License" CC0. Clinical and cognitive data are published separately on Zenodo and are not covered by this entry.

Original license text Version read: 1.0 Checked 2026-10-07

What you can do

  • Yes
  • Yes
  • Yes
  • Yes
  • Yes

What you can share

  • Yes
  • Yes
  • Yes

What you must do

  • No
  • Share alike No
  • No
  • No
  • Manuscript review No
  • Release code No
  • Return results No
  • Delete after use No

Limits

  • No
  • Location limits No

Citation

Angeles-Valdez D, Rasgado-Toledo J, Villicaña V, et al. The Mexican dataset of a repetitive transcranial magnetic stimulation clinical trial on cocaine use disorder patients: SUDMEX TMS. Scientific Data 11, 408 (2024). doi:10.1038/s41597-024-03242-y

Sources

Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.