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Open Imaging Index
MRI Brain

SUDMEX CONN (ds003346)

SUDMEX CONN: The Mexican MRI dataset of patients with cocaine use disorder

Brain MRI of 144 adults from Mexico City, people with cocaine use disorder and healthy controls, with T1w, multishell diffusion and resting-state fMRI from one 3T Philips scanner, in BIDS on OpenNeuro under CC0.

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Overview

SUDMEX CONN comes from a cross-sectional case-control study at the National Institute of Psychiatry Ramón de la Fuente Muñiz in Mexico City. The study set out to describe how crack cocaine affects the brain. It pairs brain MRI of people with cocaine use disorder (CUD) with healthy controls and was released on OpenNeuro as ds003346 in 2020 under a CC0 waiver. The data descriptor appeared in Scientific Data in 2022.

Composition

Snapshot 1.1.3 holds 144 subject folders. The participants table assigns 74 to the CUD group and 64 to the control group, leaves 6 without a group, and records age (18 to 50) and sex for most of them plus drug use variables and an exclusion flag. All 144 have a T1w scan, 141 a resting-state fMRI run and 135 a diffusion scan. Clinical and cognitive test results are published separately on Zenodo. CUD patients had to use cocaine at least three days a week and be abstinent for no more than 60 days; medical, neurological and other psychiatric disorders were exclusion criteria for everyone.

Acquisition

All scans were made between March 2015 and October 2016 on one Philips Ingenia 3T scanner with a 32-channel head coil, in a single session of about 50 minutes. The protocol was a 10-minute eyes-open resting-state EPI (TR 2 s, 3 mm voxels, 300 volumes), a mostly 1 mm isotropic 3D T1-weighted scan and a multishell HARDI diffusion scan (2 mm voxels, b = 1000 and 3000 s/mm²) with reverse phase-encoded field maps for both EPI series. Images were converted to BIDS NIfTI and defaced with pydeface.

Annotations

There are no image annotations. Diagnosis of cocaine dependence used the MINI-Plus interview. MRIQC quality reports are available on OpenNeuro.

Known limitations

  • The paper reports a final sample of 138 after removing 7 of 145 scanned people, but the release keeps 144 subjects. Its participants table flags 36 of them for exclusion with a short reason, more than the paper removed.
  • Counts in the paper disagree with each other: the text gives 75 CUD and 62 controls in one place and 74 and 64 in another, and the female counts differ between the abstract and Table 1.
  • The CUD group moved more during scanning; the authors recommend motion correction.
  • The snapshot contains a GPL v3 LICENSE file, while its dataset description declares CC0.

Cohort

Aggregate numbers from the sources below. Bars are relative to the 144 subjects.

Sex

  • Male 116 85%
  • Female 20 15%

Covers 136 of 144 subjects.

Age

mean 30.8± 7.7 · range 18 to 50
0
20
40
56
10-1920-2930-3940-4950-59

Age by sex

Reported cross table. Missing cells were not published (fewer than 10 subjects or not reported).

Female Male
  • n/a
    40-49
    14
  • n/a
    30-39
    46
  • n/a
    20-29
    48

Contrast combinations

How many subjects have exactly each set of contrasts.

T1wdwiboldSubjects with exactly this set
135
6
3

Contrast / sequence

subjects, values can overlap

  • T1-weighted 144 100%
  • BOLD fMRI 141 98%
  • Diffusion-weighted 135 94%

Condition

subjects, values can overlap

  • Cocaine use disorder 74 51%
  • Healthy control 64 44%

License and access

Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer

Access
Open download

Download without an account

Access page

Creative Commons Zero 1.0 Universal

Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.

dataset_description.json of snapshot 1.1.3 states "License" CC0. The snapshot also contains a LICENSE file with the GNU GPL v3 text next to a README titled "Addimex_Conn, Repository of the Addiction Connectome project".

Original license text Version read: 1.0 Checked 2026-10-07

What you can do

  • Yes
  • Yes
  • Yes
  • Yes

What you can share

  • Yes
  • Yes
  • Yes

What you must do

  • No
  • Share alike No
  • No
  • No
  • Manuscript review No
  • Release code No
  • Return results No
  • Delete after use No

Limits

  • No
  • Location limits No

Citation

Angeles-Valdez D, Rasgado-Toledo J, Issa-Garcia V, et al. The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder: SUDMEX CONN. Scientific Data 9, 133 (2022). doi:10.1038/s41597-022-01251-3

All numbers

Every number on this page, as stored in stats.csv, with its source.

MeasureBreakdownValueSource
Subjectstotal
144 subject folders; participants.tsv has 145 rows including sub-161 which CHANGES says was deleted (defacing problems). The paper's final sample is 138 (74 CUD and 64 HC) of 145 scanned
144ds003346-files
Subjectscondition=cocaine_use_disorder
group 2 (CUD); the paper also reports 74
74ds003346-participants
group
Subjectscondition=healthy
group 1 (HC); the paper also reports 64. 6 further subjects have no group
64ds003346-participants
group
Subjectssex=male
sex 1
116ds003346-participants
sex
Subjectssex=female
sex 2; 8 subjects have no sex
20ds003346-participants
sex
Subjectsage=10-19
all aged 18 or 19
7ds003346-participants
age
Subjectsage=20-29 56ds003346-participants
age
Subjectsage=30-39 54ds003346-participants
age
Subjectsage=40-49 18ds003346-participants
age
Subjectsage=50-59
8 subjects have no age
1ds003346-participants
age
Subjectscontrast=T1w 144ds003346-files
anat
Subjectscontrast=bold
resting state
141ds003346-files
func
Subjectscontrast=dwi
one subject has two dwi runs
135ds003346-files
dwi
Subjectscontrast_set=bold+dwi+T1w 135ds003346-files
Subjectscontrast_set=bold+T1w 6ds003346-files
Subjectscontrast_set=T1w 3ds003346-files
Subjectscondition=cocaine_use_disorder;sex=male
Table 1 of the paper reports 66
65ds003346-participants
group and sex
Subjectscondition=healthy;sex=male
Table 1 of the paper also reports 51
51ds003346-participants
group and sex
Subjectscondition=healthy;sex=female
Table 1 of the paper also reports 11
11ds003346-participants
group and sex
Subjectscondition=cocaine_use_disorder;sex=female 9angelesvaldez2022
Table 1
Subjectscondition=cocaine_use_disorder;age=20-29 29ds003346-participants
group and age
Subjectscondition=cocaine_use_disorder;age=30-39 34ds003346-participants
group and age
Subjectscondition=healthy;age=20-29 27ds003346-participants
group and age
Subjectscondition=healthy;age=30-39 20ds003346-participants
group and age
Subjectscondition=healthy;age=40-49 11ds003346-participants
group and age
Subjectssex=male;age=20-29 48ds003346-participants
sex and age
Subjectssex=male;age=30-39 46ds003346-participants
sex and age
Subjectssex=male;age=40-49 14ds003346-participants
sex and age
Subjectscondition=cocaine_use_disorder;contrast_set=bold+dwi+T1w 69ds003346-participants
group; contrast sets from the file tree
Subjectscondition=healthy;contrast_set=bold+dwi+T1w 60ds003346-participants
group; contrast sets from the file tree
Mean agetotal
136 subjects with an age
30.8ds003346-participants
age
Age SDtotal 7.7ds003346-participants
age
Median agetotal 30ds003346-participants
age
Minimum agetotal 18ds003346-participants
age
Maximum agetotal 50ds003346-participants
age
Mean agecondition=healthy
SD 8.26
30.6angelesvaldez2022
Table 1
Mean agecondition=cocaine_use_disorder
SD 7.20
31angelesvaldez2022
Table 1

Sources

The keys used in the table above.