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Open Imaging Index
MRI Brain

SUDMEX CONN (ds003346)

SUDMEX CONN: The Mexican MRI dataset of patients with cocaine use disorder

Brain MRI of people with cocaine use disorder and healthy controls, collected to describe how crack cocaine affects the brain. 144 adults from Mexico City with structural, diffusion and resting-state scans, in BIDS on OpenNeuro under CC0.

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Overview

SUDMEX CONN comes from a cross-sectional case-control study at the National Institute of Psychiatry Ramón de la Fuente Muñiz in Mexico City. The study set out to describe how crack cocaine affects the brain. It pairs brain MRI of people with cocaine use disorder (CUD) with healthy controls and was released on OpenNeuro as ds003346 in 2020 under a CC0 waiver. The data descriptor appeared in Scientific Data in 2022.

Composition

Snapshot 1.1.3 holds 144 subject folders. The participants table assigns 74 to the CUD group and 64 to the control group, leaves 6 without a group, and records age (18 to 50) and sex for most of them plus drug use variables and an exclusion flag. All 144 have a T1w scan, 141 a resting-state fMRI run and 135 a diffusion scan. Clinical and cognitive test results are published separately on Zenodo. CUD patients had to use cocaine at least three days a week and be abstinent for no more than 60 days; medical, neurological and other psychiatric disorders were exclusion criteria for everyone.

Acquisition

All scans were made between March 2015 and October 2016 on one Philips Ingenia 3T scanner with a 32-channel head coil, in a single session of about 50 minutes. The protocol was a 10-minute eyes-open resting-state EPI (TR 2 s, 3 mm voxels, 300 volumes), a mostly 1 mm isotropic 3D T1-weighted scan and a multishell HARDI diffusion scan (2 mm voxels, b = 1000 and 3000 s/mm²) with reverse phase-encoded field maps for both EPI series. Images were converted to BIDS NIfTI and defaced with pydeface.

Annotations

There are no image annotations. Diagnosis of cocaine dependence used the MINI-Plus interview. MRIQC quality reports are available on OpenNeuro.

Known limitations

  • The paper reports a final sample of 138 after removing 7 of 145 scanned people, but the release keeps 144 subjects. Its participants table flags 36 of them for exclusion with a short reason, more than the paper removed.
  • Counts in the paper disagree with each other: the text gives 75 CUD and 62 controls in one place and 74 and 64 in another, and the female counts differ between the abstract and Table 1.
  • The CUD group moved more during scanning; the authors recommend motion correction.
  • The snapshot contains a GPL v3 LICENSE file, while its dataset description declares CC0.

Cohort

Aggregate numbers from the sources below. Bars are relative to the 144 subjects.

Sex

  • Female 20 15%
  • Male 116 85%

Covers 136 of 144 subjects.

sex in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns

Contrast / sequence

Groups can overlap

  • T1-weighted 144 100%
  • BOLD fMRI 141 98%
  • Diffusion-weighted 135 94%

anat, func, dwi in File tree of ds003346 snapshot 1.1.3 (CC0), subjects with a T1w, dwi or bold NIfTI file

Age by condition

Reported cross table. A dot marks a cell the source does not give.

Cocaine use disorderHealthy control
20-292927
30-393420
40-49·11

group and age in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns

Age

mean 30.8 ± 7.7, median 30, range 18 to 50

0
20
40
56
10-1920-2930-3940-4950-59

age in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns

Condition

Groups can overlap

  • Cocaine use disorder 74 51%
    Age mean 31
  • Healthy control 64 44%
    Age mean 30.6

group in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns; Table 1 in Angeles-Valdez et al. 2022, The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder, Scientific Data

Condition by sex

Reported cross table. A dot marks a cell the source does not give.

FemaleMale
Cocaine use disorder965
Healthy control1151

group and sex in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns; Table 1 in Angeles-Valdez et al. 2022, The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder, Scientific Data

Age by sex

Reported cross table. Missing cells were not published (fewer than 10 or not reported).

Female Male
  • n/a
    40-49
    14
  • n/a
    30-39
    46
  • n/a
    20-29
    48

sex and age in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns

Contrast combinations

How many subjects have exactly each set of contrasts.

T1wdwiboldSubjects with exactly this set
135
6
3

From File tree of ds003346 snapshot 1.1.3 (CC0), subjects with a T1w, dwi or bold NIfTI file

Other reported numbers 2
Subjects · Cocaine use disorder, BOLD fMRI + Diffusion-weighted + T1-weighted 69group; contrast sets from the file tree in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns
Subjects · Healthy control, BOLD fMRI + Diffusion-weighted + T1-weighted 60group; contrast sets from the file tree in participants.tsv of ds003346 snapshot 1.1.3 (CC0), counted over the 144 rows with an image folder; group, sex and age columns

License and access

Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer

Access
Open download

Download without an account

Access page

Creative Commons Zero 1.0 Universal

Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.

dataset_description.json of snapshot 1.1.3 states "License" CC0. The snapshot also contains a LICENSE file with the GNU GPL v3 text next to a README titled "Addimex_Conn, Repository of the Addiction Connectome project".

Original license text Version read: 1.0 Checked 2026-10-07

What you can do

  • Yes
  • Yes
  • Yes
  • Yes
  • Yes

What you can share

  • Yes
  • Yes
  • Yes

What you must do

  • No
  • Share alike No
  • No
  • No
  • Manuscript review No
  • Release code No
  • Return results No
  • Delete after use No

Limits

  • No
  • Location limits No

Citation

Angeles-Valdez D, Rasgado-Toledo J, Issa-Garcia V, et al. The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder: SUDMEX CONN. Scientific Data 9, 133 (2022). doi:10.1038/s41597-022-01251-3

Sources

Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.