SLIM
Southwest University Longitudinal Imaging Multimodal Brain Data Repository
Longitudinal test-retest MRI of 594 healthy Chinese undergraduates scanned up to three times over about three and a half years at 3 T: T1-weighted MPRAGE, resting-state fMRI and diffusion imaging, with behavioral and QA measures.
Overview
The Southwest University Longitudinal Imaging Multimodal (SLIM) repository follows healthy Chinese undergraduates with repeated brain MRI over roughly three and a half years. Jiang Qiu's group at the Brain Imaging Center of Southwest University in Chongqing collected it between November 2011 and January 2015 and released it through the International Neuroimaging Data-sharing Initiative (INDI) with a Scientific Data descriptor in 2017. Its narrow age range and long retest interval make it a resource for test-retest reliability and for tracking brain change in early adulthood.
Composition
The phenotype files list 594 participants and 1,048 sessions: 580 at the first time point, 240 at the second and 228 at the third. 121 participants have all three sessions. At the first scan the mean age was 20.1 years (range 17 to 27). Each session holds a T1-weighted image, a resting-state fMRI run and a diffusion scan, with a few sessions missing one of the latter two. Released behavioral measures include depression and anxiety inventories. QA metrics from the Preprocessed Connectomes Project protocol and parcellated connectivity matrices (Dosenbach 160 and Shen 268 atlases) are also provided.
Acquisition
All sessions used one 3 T Siemens Trio. The MPRAGE has 176 slices of 1 mm isotropic voxels, TR 1900 ms, TE 2.52 ms and TI 900 ms. The eight-minute eyes-closed resting-state run has 242 EPI volumes of 32 slices, TR 2000 ms, TE 30 ms and 3.4 x 3.4 x 3 mm voxels with a 1 mm gap. Diffusion was a spin-echo EPI at 2 mm isotropic with 30 directions at b = 1000 s/mm², repeated three times for 93 volumes in total. Faces were removed from the anatomical images.
Annotations
There are no image labels. Phenotypes cover age, sex, scan dates and questionnaire scores.
Known limitations
- Single site and single scanner, and a narrow age range of university students.
- The paper's counts per number of sessions add up to 595 participants, while the phenotype files list 594.
- Fourteen participants have no first-time-point session, so their age is not given.
- Task fMRI was acquired for some participants but is not released, and only part of the behavioral battery is shared.
- Images were released regardless of quality; users apply their own exclusions.
- Some sessions of the first two time points were shared earlier as part of CoRR.
Cohort
Aggregate numbers from the sources below. Bars are relative to the 594 subjects.
Sex
- Female 330 56%
- Male 264 44%
Age
mean 20.08± 1.3 · range 17 to 27Age by sex
Reported cross table. Missing cells were not published (fewer than 10 subjects or not reported).
- 20120-29190
- 12210-1967
Contrast / sequence
subjects, values can overlap
- T1-weighted 594 100%
- Diffusion-weighted 594 100%
- BOLD fMRI 592 100%
License and access
Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer
Download without an account
1000 Functional Connectomes Project / INDI terms (Creative Commons Attribution Non-Commercial, no version stated)
Non-commercial use only, after registering with the 1000 Functional Connectomes Project on NITRC. The NITRC project lists a Creative Commons Attribution Non-Commercial license without a version: derived works must credit the source and stay non-commercial but need not use the same license.
The release page states "Creative Commons License: Attribution - Non-Commercial" as its usage agreement, and the data descriptor names CC-BY-NC as the data license. The images and phenotype files download from the public fcp-indi S3 bucket without an account. The data descriptor asks users to cite it and acknowledge the original authors and lab.
What you can do
- No
- Not stated
- Not stated
- Conditional
- Not stated
What you can share
- Not stated
- Conditional
- Share trained models Not stated
What you must do
- Yes
- No
- Conditional
- Ethics approval No
- Manuscript review No
- Release code No
- Return results No
- Delete after use No
Limits
- No
- Location limits No
Commercial license: Not stated
Citation
Liu W, Wei D, Chen Q, Yang W, Meng J, Wu G, Bi T, Zhang Q, Zuo XN, Qiu J. Longitudinal test-retest neuroimaging data from healthy young adults in southwest China. Scientific Data 4, 170017 (2017). doi:10.1038/sdata.2017.17
All numbers
Every number on this page, as stored in stats.csv, with its source.
| Measure | Breakdown | Value | Source |
|---|---|---|---|
| Subjects | total unique ids; the paper gives 121 subjects with three sessions, 211 with two and 263 with one, which adds up to 595 | 594 | slim-phenodata column Match_ID in all three files |
| Studies | total 580, 240 and 228 sessions at time points 1, 2 and 3, the same as the paper | 1,048 | slim-phenodata rows of all three files |
| Subjects | sex=female | 330 | slim-phenodata column Sex |
| Subjects | sex=male four rows carry stray characters after the word male and are counted as male | 264 | slim-phenodata column Sex |
| Subjects | contrast=T1w MPRAGE in at least one session | 594 | slim-phenodata column anat |
| Subjects | contrast=bold 8-minute resting-state scan in at least one session | 592 | slim-phenodata column func |
| Subjects | contrast=dwi 30-direction DTI in at least one session | 594 | slim-phenodata column DTI |
| Studies | contrast=T1w | 1,048 | slim-phenodata column anat |
| Studies | contrast=bold | 1,045 | slim-phenodata column func |
| Studies | contrast=dwi | 1,029 | slim-phenodata column DTI |
| Studies | contrast_set=bold+dwi+T1w | 1,026 | slim-phenodata columns anat, func and DTI |
| Studies | contrast_set=bold+T1w | 19 | slim-phenodata columns anat, func and DTI |
| Studies | contrast_set=dwi+T1w | 3 | slim-phenodata columns anat, func and DTI |
| Subjects | age=10-19 age at the first scan; only the 580 subjects scanned at time point 1 have an age | 189 | slim-phenodata swu_slim_phenodata_time1.tsv column age_at_Scan1 |
| Subjects | age=20-29 age at the first scan | 391 | slim-phenodata swu_slim_phenodata_time1.tsv column age_at_Scan1 |
| Subjects | sex=female;age=10-19 age at the first scan | 122 | slim-phenodata swu_slim_phenodata_time1.tsv columns Sex and age_at_Scan1 |
| Subjects | sex=male;age=10-19 age at the first scan | 67 | slim-phenodata swu_slim_phenodata_time1.tsv columns Sex and age_at_Scan1 |
| Subjects | sex=female;age=20-29 age at the first scan | 201 | slim-phenodata swu_slim_phenodata_time1.tsv columns Sex and age_at_Scan1 |
| Subjects | sex=male;age=20-29 age at the first scan | 190 | slim-phenodata swu_slim_phenodata_time1.tsv columns Sex and age_at_Scan1 |
| Minimum age | total at time point 1 | 17 | liu2017 Methods: Overall design |
| Maximum age | total at time point 1 | 27 | liu2017 Methods: Overall design |
| Mean age | total at time point 1 | 20.1 | liu2017 Methods: Overall design |
| Median age | total at time point 1 | 20 | liu2017 Methods: Overall design |
| Age SD | total at time point 1 | 1.3 | slim-phenodata swu_slim_phenodata_time1.tsv column age_at_Scan1 |
Sources
The keys used in the table above.
- liu2017 Liu et al. 2017, Longitudinal test-retest neuroimaging data from healthy young adults in southwest China, Scientific Data paper
- indi-slim-page SWU SLIM release page, FCP/INDI Retrospective website
- slim-phenodata Phenotype files swu_slim_phenodata_time1.tsv, swu_slim_phenodata_time2.tsv and swu_slim_phenodata_time3.tsv (CC BY-NC per the release page) in the public SLIM folder of the fcp-indi S3 bucket computed