TCGA-OV
The Cancer Genome Atlas Ovarian Cancer Collection
Pre-surgical and follow-up clinical CT, plus MRI of one patient, of 143 women with ovarian serous cystadenocarcinoma from eight US centers, matched by patient ID to the TCGA clinical, genomic and pathology data for radiogenomics.
Overview
TCGA-OV is the radiology part of The Cancer Genome Atlas project on ovarian serous cystadenocarcinoma. The Cancer Imaging Archive hosts the clinical scans of TCGA patients under the same patient identifiers used in TCGA, so the images can be linked to the clinical, genomic and histopathology records in the NCI Genomic Data Commons. The collection supports radiogenomics studies that relate tumor appearance on imaging to molecular subtype and outcome.
Composition
Version 4 holds 143 patients with 322 imaging studies, 844 DICOM series and 53,662 images, about 28.3 GB. Counted from the open series metadata file, every patient has CT and a single patient also has one MRI study; one further series is a non-image summary series (modality OT). All patients are female. Most patients have one study, while some have a longer series of scans over time. The collection page links a shared list of cases with both a pre-operative and an early post-operative CT, aimed at judging how complete the surgical debulking was. A clinical data snapshot from January 2016 is linked from the collection page, and current clinical and genomic records live in the GDC.
Acquisition
For each TCGA case, the baseline imaging on TCIA is pre-surgical. Scans come from routine care rather than a research protocol, so scanners, protocols and series differ between patients. Eight US sites contributed, among them the University of Pittsburgh, Washington University, MD Anderson, Memorial Sloan-Kettering and Mayo Clinic. Most CT studies cover the abdomen and pelvis, some also the chest. Scanners are mostly GE and Siemens, with a few Philips, Toshiba and Imatron systems. The one MRI study includes T1-weighted pre- and post-contrast, T2-weighted and diffusion-weighted series. DICOM dates are shifted by a fixed offset per site, which keeps intervals between a patient's studies.
Known limitations
- No image annotations or segmentations are distributed with the collection itself.
- MRI covers a single patient, so the collection is in practice a CT dataset.
- Contrast phases, slice thickness and scanner settings vary and are not documented on the collection page.
- Clinical dates in TCGA count from the diagnosis date, while DICOM dates use a different offset, so the two timelines are not aligned.
- Age is read from DICOM headers and is missing for two patients.
Cohort
Aggregate numbers from the sources below. Bars are relative to the 143 subjects.
Sex
- Female 143 100%
Age
Modality
subjects
- CT 143 100%
- MRI 1 <1%
Scanner vendor
subjects
- GE HealthCare 111 78%
- Siemens Healthineers 45 31%
- Other 5 3%
- Philips 2 1%
- Canon Medical 2 1%
License and access
Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer
Download without an account
Images download with the TCIA Data Retriever. Clinical, genomic and histopathology data for the same patient IDs are held in the NCI Genomic Data Commons; a 2016 clinical data snapshot is linked from the collection page.
Creative Commons Attribution 3.0 Unported
Older version of CC BY. Use, share and adapt the data for any purpose, including commercial use, as long as you credit the creators.
What you can do
- Yes
- Yes
- Yes
- Yes
What you can share
- Yes
- Yes
- Yes
What you must do
- Yes
- Share alike No
- No
- No
- Manuscript review No
- Release code No
- Return results No
- Delete after use No
Limits
- No
- Location limits No
Citation
Holback C, Jarosz R, Prior F, Mutch DG, Bhosale P, Garcia K, Lee Y, Kirk S, Sadow CA, Levine S, Sala E, Elnajjar P, Morgan T, Erickson BJ. (2016). The Cancer Genome Atlas Ovarian Cancer Collection (TCGA-OV) (Version 4) [Data set]. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2016.NDO1MDFQ
All numbers
Every number on this page, as stored in stats.csv, with its source.
| Measure | Breakdown | Value | Source |
|---|---|---|---|
| Subjects | total | 143 | tcia-tcga-ov Data Access table |
| Studies | total | 322 | tcia-tcga-ov Data Access table |
| Scans | total DICOM series | 844 | tcia-tcga-ov Data Access table |
| Images | total DICOM images (slices) | 53,662 | tcia-tcga-ov Data Access table |
| Subjects | modality=CT | 143 | tcia-tcga-ov-digest Modality; Patient ID |
| Subjects | modality=MR | 1 | tcia-tcga-ov-digest Modality; Patient ID |
| Studies | modality=CT | 321 | tcia-tcga-ov-digest Modality; Study Instance UID |
| Studies | modality=MR | 1 | tcia-tcga-ov-digest Modality; Study Instance UID |
| Scans | modality=CT DICOM series | 820 | tcia-tcga-ov-digest Modality |
| Scans | modality=MR DICOM series | 23 | tcia-tcga-ov-digest Modality |
| Subjects | sex=female DICOM header value | 143 | tcia-tcga-ov-digest Patient Sex; Patient ID |
| Subjects | age=30-39 age at the earliest study; 2 patients have no age in the header | 2 | tcia-tcga-ov-digest Patient Age; Patient ID |
| Subjects | age=40-49 age at the earliest study | 24 | tcia-tcga-ov-digest Patient Age; Patient ID |
| Subjects | age=50-59 age at the earliest study | 40 | tcia-tcga-ov-digest Patient Age; Patient ID |
| Subjects | age=60-69 age at the earliest study | 40 | tcia-tcga-ov-digest Patient Age; Patient ID |
| Subjects | age=70-79 age at the earliest study | 30 | tcia-tcga-ov-digest Patient Age; Patient ID |
| Subjects | age=80-89 age at the earliest study | 5 | tcia-tcga-ov-digest Patient Age; Patient ID |
| Subjects | vendor=ge patients with at least one GE series | 111 | tcia-tcga-ov-digest Manufacturer; Patient ID |
| Subjects | vendor=siemens patients with at least one Siemens series (SIEMENS, Siemens) | 45 | tcia-tcga-ov-digest Manufacturer; Patient ID |
| Subjects | vendor=philips patients with at least one Philips series | 2 | tcia-tcga-ov-digest Manufacturer; Patient ID |
| Subjects | vendor=canon Toshiba | 2 | tcia-tcga-ov-digest Manufacturer; Patient ID |
| Subjects | vendor=other Imatron electron-beam CT | 5 | tcia-tcga-ov-digest Manufacturer; Patient ID |
Sources
The keys used in the table above.
- tcia-tcga-ov TCIA TCGA-OV collection page (version 4, updated 2020/05/29) website
- tcia-tcga-ov-digest TCIA TCGA-OV series metadata digest (XLSX linked from the collection page, open, no login, CC BY 3.0), counted per Patient ID, Study Instance UID, Modality, Patient Sex, Patient Age and Manufacturer computed