Stress CMR strain and outcomes (Monzino)

A retrospective cohort of patients with stable symptoms that raised suspicion of myocardial ischemia, all examined with dipyridamole stress cardiac MRI. The study tested whether feature-tracking strain measured under stress predicts long-term major adverse cardiac events, and whether a contrast-free protocol with strain could match the prognostic value of perfusion imaging. The related raw data sit in a restricted Zenodo record that has to be requested from its owners.

Composition

729 consecutive patients with known or suspected coronary artery disease were included. Mean age was 63 years (SD 10) and 616 were men. Mean follow-up was 5.8 years (SD 1.2), during which 70 patients had a major adverse cardiac event, defined as nonfatal myocardial infarction or cardiac death.

Acquisition

Every patient had stress cardiac MRI with dipyridamole, including assessment of perfusion, left ventricular ejection fraction and late gadolinium enhancement. Feature-tracking analysis gave the two-dimensional global peak circumferential strain for each patient. Centres, scanners, field strength and sequence parameters are not stated in the abstract or the record; the corresponding author is at Centro Cardiologico Monzino in Milan.

Annotations

Per-patient strain values, late gadolinium enhancement presence and outcome events over follow-up. No image-level labels are described.

Known limitations

The record lists no files, so it is unclear whether it holds CMR images or only the tabular measurements and outcomes. The cohort is mostly male. Only abstract-level facts are public, so the acquisition protocol is unknown. Access is at the owners' discretion even though the record carries a CC BY 4.0 label.