Singapore Dyscalculia fMRI (Kwok et al. 2023)
Kwok et al., 2023, Human Brain Mapping
Task fMRI and T1-weighted brain MRI of Singaporean children aged 8 to 9 with persistent developmental dyscalculia and typically achieving peers, collected to compare brain activation during arithmetic, number matching and visuo-spatial working memory tasks.
Overview
This OpenNeuro dataset holds the raw MRI behind Kwok et al. (2023), a pre-registered task fMRI study that compared children with persistent developmental dyscalculia (DD) against typically achieving (TA) classmates in Singapore. The children came from a longitudinal cohort that had been followed with cognitive testing from kindergarten to Grade 1, and they were scanned in Grade 3. The study found no consistent group differences in brain activation for any of its three tasks. The data are released under CC0.
Composition
68 children were scanned successfully out of 77 enrolled: 30 in the DD group and 38 in the TA group, with a mean age of 8.95 years (SD 0.34) and 30 boys. The DD group combined children placed in a national learning support program for math with children who scored in the bottom 10th percentile of a standardized math test in Grade 1. Each child has one T1-weighted scan and up to six BOLD runs: two each of an arithmetic task, a matching task with numbers, faces and shapes, and a dot-matrix visuo-spatial working memory task. Event files with trial timings come with every run. The group label is the only column in participants.tsv.
Acquisition
All scans were made on one Siemens 3T MAGNETOM Prisma with a 32-channel head coil at Nanyang Technological University. The T1-weighted MPRAGE has 0.9 mm isotropic voxels. The functional runs are T2*-weighted echo-planar images with a repetition time of 1 s, 48 interleaved slices and 2.5 mm isotropic voxels. The files are organized in BIDS.
Known limitations
The dataset README mentions field maps, but snapshot 1.0.0 contains no fmap folders. Some children are missing single task runs. The paper excluded further children from individual task analyses for low accuracy, so the analysed sample per task is smaller than 68. Cognitive and math test scores used to form the groups are not part of the release. All children come from one city and one scanner.
Cohort
Aggregate numbers from the sources below. Bars are relative to the 68 subjects.
Sex
- Female 38 56%
- Male 30 44%
Section 2.1 in Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping; PatientSex in BIDS file tree of ds004791 snapshot 1.0.0 (CC0), raw NIfTI files under sub-*/ counted per suffix, sex and age from PatientSex and PatientAge in the T1w JSON sidecars
Contrast / sequence
Groups can overlap
- T1-weighted 68 100%
- BOLD fMRI 68 100%
Scanner vendor
- Siemens Healthineers 68 100%
Section 2.4 in Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping
Country
- Singapore 68 100%
Section 2.2 in Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping
Age
mean 9 ± 0.3
PatientAge in BIDS file tree of ds004791 snapshot 1.0.0 (CC0), raw NIfTI files under sub-*/ counted per suffix, sex and age from PatientSex and PatientAge in the T1w JSON sidecars; Section 2.1 in Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping
Condition
Groups can overlap
- Healthy control 38 56%
- Dyscalculia 30 44%
Section 2.2 in Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping; group in participants.tsv of ds004791 snapshot 1.0.0 (CC0), counted per row; groups from group
Field strength
- 3 T 68 100%
Section 2.4 in Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping
Contrast combinations
How many subjects have exactly each set of contrasts.
| T1w | bold | Subjects with exactly this set |
|---|---|---|
68 |
License and access
Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer
Download without an account
Creative Commons Zero 1.0 Universal
Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.
dataset_description.json of snapshot 1.0.0 states "License" CC0.
What you can do
- Yes
- Yes
- Yes
- Yes
- Yes
What you can share
- Yes
- Yes
- Yes
What you must do
- No
- Share alike No
- No
- No
- Manuscript review No
- Release code No
- Return results No
- Delete after use No
Limits
- No
- Location limits No
Citation
Kwok FY, Wilkey ED, Peters L, Khiu E, Bull R, Lee K, Ansari D. Developmental dyscalculia is not associated with atypical brain activation: A univariate fMRI study of arithmetic, magnitude processing, and visuospatial working memory. Human Brain Mapping 44(18), 6308-6325 (2023). doi:10.1002/hbm.26495
Sources
Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.
- Kwok et al. 2023, Developmental dyscalculia is not associated with atypical brain activation, Human Brain Mapping paper
- OpenNeuro ds004791 snapshot 1.0.0 (dataset_description.json, README, CHANGES and snapshot size) website
- participants.tsv of ds004791 snapshot 1.0.0 (CC0), counted per row; groups from group computed
- BIDS file tree of ds004791 snapshot 1.0.0 (CC0), raw NIfTI files under sub-*/ counted per suffix, sex and age from PatientSex and PatientAge in the T1w JSON sidecars computed