Older Age Prototype and Exemplar fMRI (ds006686)
Effects of older age on neural prototype and exemplar correlates
Structural MRI (T1w, T2w), resting-state fMRI and four runs of category-learning task fMRI from 36 healthy young and 28 healthy older adults, collected to compare prototype and exemplar learning across age. BIDS, CC0.
Overview
This OpenNeuro dataset comes from a University of Oregon study of how ageing changes concept learning. Young and older adults first learned two categories of cartoon animals outside the scanner, then sorted old and new animals without feedback during fMRI. The authors fitted prototype and exemplar models to the choices and the brain signal to ask whether older adults rely more on abstracted category centres than on memory for single examples. The first snapshot appeared in September 2025; snapshot 1.0.3 (March 2026) adds the linked paper and is released under a CC0 waiver.
Composition
The release holds 64 participants with one session each: 36 young adults aged 18 to 27 and 28 older adults aged 62 to 86. These are the participants retained for analysis in the paper; it reports recruiting 42 young and 40 older adults and excluding the rest for scan problems or highly correlated model regressors. Every participant has a T1-weighted image, a T2-weighted image, one resting-state run and four category-learning runs. The participants file gives age, age group, sex, race and ethnicity.
Acquisition
All scans were acquired on one Siemens MAGNETOM Skyra 3T scanner with a 32-channel head coil at the Lewis Center for Neuroimaging. The structural scan is a 1 mm isotropic MPRAGE. The T2-weighted image is a coronal acquisition at 0.4 x 0.4 x 2 mm, angled perpendicular to the long axis of the hippocampus. Functional runs use a multiband (factor 3) gradient-echo EPI sequence with TR 2 s, TE 25 ms and 2 mm slices. The resting-state run lasted 6 minutes with eyes open on a fixation cross. Images were defaced.
Annotations
There are no image annotations. Each task run has an events file with trial-level stimulus features, distance from the prototype, old or new status, responses and reaction times. A code folder holds the behavioural model fitting and FSL analysis scripts.
Known limitations
- Participants are healthy and screened; there is no clinical group.
- The age distribution is bimodal, with no participants between 28 and 61.
- The paper excluded some individual task runs for correlated regressors or head motion; all runs are shared, so users must apply their own quality control.
Cohort
Aggregate numbers from the sources below. Bars are relative to the 64 subjects.
Sex
- Female 39 61%
- Male 25 39%
sex in participants.tsv of the ds006686 BIDS repository (CC0), columns age, group and sex
Condition
Groups can overlap
- Healthy control 64 100%
Methods, Participants in Bowman and Zeithamova 2026, Neurobiology of Aging 162:66-80
Scanner vendor
- Siemens Healthineers 64 100%
Methods, MRI data acquisition in Bowman and Zeithamova 2026, Neurobiology of Aging 162:66-80
Country
- United States 64 100%
Methods, MRI data acquisition in Bowman and Zeithamova 2026, Neurobiology of Aging 162:66-80
Age
mean 42.2 ± 25.2, median 22.5, range 18 to 86
age in participants.tsv of the ds006686 BIDS repository (CC0), columns age, group and sex
Contrast / sequence
Groups can overlap
- T1-weighted 64 100%
- T2-weighted 64 100%
- BOLD fMRI 64 100%
anat/*_T1w.nii.gz, anat/*_T2w.nii.gz, func/*_bold.nii.gz in File listing and JSON sidecars of the ds006686 BIDS repository (CC0), NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionAddress
Field strength
- 3 T 64 100%
Methods, MRI data acquisition in Bowman and Zeithamova 2026, Neurobiology of Aging 162:66-80
Contrast combinations
How many subjects have exactly each set of contrasts.
| T1w | T2w | bold | Subjects with exactly this set |
|---|---|---|---|
64 |
anat and func NIfTI files in File listing and JSON sidecars of the ds006686 BIDS repository (CC0), NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionAddress
License and access
Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer
Download without an account
Creative Commons Zero 1.0 Universal
Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.
dataset_description.json of snapshot 1.0.3 states "License" CC0.
What you can do
- Yes
- Yes
- Yes
- Yes
- Yes
What you can share
- Yes
- Yes
- Yes
What you must do
- No
- Share alike No
- No
- No
- Manuscript review No
- Release code No
- Return results No
- Delete after use No
Limits
- No
- Location limits No
Citation
Bowman CR, Zeithamova D. Ventromedial prefrontal cortex supports prototype representations in healthy older adults. Neurobiology of Aging 162:66-80 (2026). doi:10.1016/j.neurobiolaging.2026.02.006
Sources
Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.
- OpenNeuro ds006686 snapshot 1.0.3 (dataset_description.json, README.txt, CHANGES, snapshot list and snapshot size) website
- participants.tsv of the ds006686 BIDS repository (CC0), columns age, group and sex computed
- File listing and JSON sidecars of the ds006686 BIDS repository (CC0), NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionAddress computed
- Bowman and Zeithamova 2026, Neurobiology of Aging 162:66-80 paper