Adult Dyslexia Functional and Structural MRI (ds005577)
Functional and structural differences in adults with dyslexia
Structural, diffusion and task fMRI of young adults with and without dyslexia, collected in Ghent to compare brain structure and language-task activation between groups. 70 participants (35 dyslexia, 35 controls) in BIDS under CC0.
Overview
This OpenNeuro dataset comes from a Ghent study that compared brain structure and language-related brain activity between young adults with dyslexia and typical readers. Each participant was scanned once at Ghent University Hospital between November 2021 and May 2022. Snapshot 1.0.0 was published in December 2024 under a CC0 waiver. The work was funded by the Flemish Research Fund (FWO, grant 1217621N).
Composition
The release holds 70 participants: 35 with a dyslexia diagnosis made by a trained professional and 35 without any diagnosed language or reading impairment. All were right-handed native Dutch speakers without brain injury or neurological disease. Ages range from 17 to 37 years and the participants file lists 43 women and 27 men. Every participant has a T1-weighted scan, a diffusion series and three task fMRI runs, plus field maps.
Acquisition
All images come from a single Siemens Prisma Fit 3T scanner. The structural scan is an MPRAGE with 1 mm slices. Diffusion was acquired with multiband echo-planar imaging at 2 mm slices with anterior-posterior phase encoding, plus one reverse phase-encoded b0 image for distortion correction. The functional runs (TR 1.07 s, multiband factor 4, 2.5 mm slices) cover three block-design tasks: covert letter fluency, visual rhyme decision and lexical decision. A phase-difference field map with two magnitude images is included for the functional data. Task scripts and stimuli are hosted separately on OSF.
Annotations
There are no image annotations. Each task has one top-level events file that describes the block design for all participants. The participants file gives group, age, sex and writing hand.
Known limitations
- No paper describing the cohort is linked from the dataset, and several metadata fields still hold template text.
- The README lists diffusion shells of 0, 1200 and 3000 s/mm², while the shipped b-value file of the inspected subject lists 0, 1000 and 3000.
- One participant is 17, although the README gives 18 to 40 years as the inclusion range.
- The structural images are not labelled as defaced.
- No reading or cognitive test scores are shared.
Cohort
Aggregate numbers from the sources below. Bars are relative to the 70 subjects.
Sex
- Female 43 61%
- Male 27 39%
participants.tsv: sex in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Contrast / sequence
Groups can overlap
- T1-weighted 70 100%
- Diffusion-weighted 70 100%
- BOLD fMRI 70 100%
sub-*/anat/*_T1w.nii.gz, sub-*/dwi/*_dwi.nii.gz, sub-*/func/*_bold.nii.gz in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Condition by sex
Reported cross table. A dot marks a cell the source does not give.
| Female | Male | |
|---|---|---|
| Dyslexia | 21 | 14 |
| Healthy control | 22 | 13 |
participants.tsv: group and sex in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Contrast / sequence by field strength
ScansReported cross table. A dot marks a cell the source does not give.
| 3 T | |
|---|---|
| T1-weighted | 70 |
T1w sidecars: MagneticFieldStrength in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Age
participants.tsv: age in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Condition
Groups can overlap
- Dyslexia 35 50%
- Healthy control 35 50%
README: Participants in OpenNeuro ds005577 snapshot 1.0.0 (README, dataset_description.json, CHANGES and snapshot summary)
Contrast / sequence by scanner vendor
ScansReported cross table. A dot marks a cell the source does not give.
| Siemens Healthineers | |
|---|---|
| T1-weighted | 70 |
T1w sidecars: Manufacturer in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Contrast / sequence by country
ScansReported cross table. A dot marks a cell the source does not give.
| Belgium | |
|---|---|
| T1-weighted | 70 |
T1w sidecars: InstitutionName in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
Contrast combinations
How many subjects have exactly each set of contrasts.
| T1w | dwi | bold | Subjects with exactly this set |
|---|---|---|---|
70 |
anat, dwi and func folders in File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName
License and access
Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer
Download without an account
Creative Commons Zero 1.0 Universal
Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.
dataset_description.json of snapshot 1.0.0 states "License" CC0.
What you can do
- Yes
- Yes
- Yes
- Yes
- Yes
What you can share
- Yes
- Yes
- Yes
What you must do
- No
- Share alike No
- No
- No
- Manuscript review No
- Release code No
- Return results No
- Delete after use No
Limits
- No
- Location limits No
Citation
Verhelst H, Karlsson E, Gerrits R, Vingerhoets G. Functional and structural differences in adults with dyslexia. OpenNeuro, version 1.0.0 (2024). doi:10.18112/openneuro.ds005577.v1.0.0
Sources
Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.
- OpenNeuro ds005577 snapshot 1.0.0 (README, dataset_description.json, CHANGES and snapshot summary) website
- File tree, participants.tsv and JSON sidecars of ds005577 snapshot 1.0.0 (CC0), raw NIfTI files counted per subject folder, sidecar fields Manufacturer, ManufacturersModelName, MagneticFieldStrength and InstitutionName computed