HRV-ER (ds003823)
Heart rate variability biofeedback training and emotion regulation
Brain MRI, functional MRI, arterial spin labeling and MR spectroscopy from healthy younger and older adults, scanned before and after a randomized 5-week trial of heart rate variability biofeedback to study emotion regulation. With physiology, cognition and mood questionnaires.
Overview
HRV-ER is the shared data of a randomized clinical trial at the University of Southern California (NCT03458910) that asked whether training people to raise their heart rate oscillations changes how the brain handles emotion. Healthy younger and older adults practiced heart rate variability biofeedback twice a day for five weeks, either with slow paced breathing to increase oscillations or with individual strategies to decrease them. Brain MRI was taken before and after the training. The release on OpenNeuro is in BIDS under CC0 and is described in a data paper in Scientific Data (2023).
Composition
The paper reports 121 younger (18 to 35 years) and 72 older (55 to 80 years) participants, recruited between 2018 and 2020. participants.tsv lists all 193 with sex, handedness, age group and trial arm, plus flags for which measures exist and which ones the authors recommend excluding. Image files exist for 176 participants: 176 have a pre-intervention session and 151 a post-intervention session. Besides imaging, the dataset holds mood and anxiety questionnaires, cognitive tests, a stress task with physiological recordings, home and lab biofeedback recordings, wristband sleep estimates and, for a subset, plasma amyloid and tau.
Acquisition
All scans come from one 3 T Siemens MAGNETOM Trio with a 32-channel head coil. Each session has a 1 mm MPRAGE, a multi-echo BOLD resting-state run and an emotion regulation task run, a pCASL resting scan with an M0 image, a high-resolution turbo spin echo scan of 11 axial slices for locus coeruleus contrast, and single-voxel MR spectroscopy of the anterior cingulate cortex. The post session adds an ultimatum game run and BOLD and pCASL runs while participants repeated their training. Physiological signals were recorded during scanning. MRS raw data are shared as Siemens IMA files with a table of metabolite levels.
Annotations
There are no image annotations. Task events, MRIQC and FreeSurfer quality metrics, and per-scan exclusion recommendations are included.
Known limitations
- 17 of the 193 listed participants have no image files.
- T1-weighted scans are defaced.
- 25 of the 176 imaged participants have no post-intervention session.
- The locus coeruleus turbo spin echo scans are stored with the BIDS suffix T1w (acq-lc), next to the whole-brain MPRAGE (acq-wholebrain).
Cohort
Aggregate numbers from the sources below. Bars are relative to the 193 subjects.
Sex
- Female 106 55%
- Male 87 45%
gender in participants.tsv of ds003823 snapshot 1.3.5 (CC0), counted per row
Modality
- MRI 176 91%
sub-*/ses-*/*/*.nii* in File tree of ds003823 snapshot 1.3.5 (CC0), NIfTI files counted per subject, session and BIDS suffix
Condition
Groups can overlap
- Healthy control 193 100%
Methods: Participants in Yoo et al. 2023, Multimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial, Scientific Data
Age
Methods: Participants in Yoo et al. 2023, Multimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial, Scientific Data
Contrast / sequence
Groups can overlap
- T1-weighted 176 91%
- BOLD fMRI 176 91%
- Arterial spin labeling 173 90%
sub-*/ses-*/anat/*_T1w.nii.gz, sub-*/ses-*/func/*_bold.nii.gz, sub-*/ses-*/perf/*_asl.nii in File tree of ds003823 snapshot 1.3.5 (CC0), NIfTI files counted per subject, session and BIDS suffix
Age by sex
Reported cross table. Missing cells were not published (fewer than 10 or not reported).
- 4555-8027
- 6118-3560
gender, age_group in participants.tsv of ds003823 snapshot 1.3.5 (CC0), counted per row
Contrast combinations
How many subjects have exactly each set of contrasts.
| T1w | bold | asl | Subjects with exactly this set |
|---|---|---|---|
173 | |||
3 |
anat, func and perf folders in File tree of ds003823 snapshot 1.3.5 (CC0), NIfTI files counted per subject, session and BIDS suffix
License and access
Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer
Download without an account
Creative Commons Zero 1.0 Universal
Public domain dedication. Do anything with the data, including commercial use, without asking and without having to give credit.
dataset_description.json of snapshot 1.3.5 states "License" CC0.
What you can do
- Yes
- Yes
- Yes
- Yes
- Yes
What you can share
- Yes
- Yes
- Yes
What you must do
- No
- Share alike No
- No
- No
- Manuscript review No
- Release code No
- Return results No
- Delete after use No
Limits
- No
- Location limits No
Citation
Yoo HJ, Nashiro K, Min J, Cho C, Mercer N, Bachman SL, Nasseri P, Dutt S, Porat S, Choi P, Zhang Y, Grigoryan V, Feng T, Thayer JF, Lehrer P, Chang C, Stanley JA, Marmarelis VZ, Narayanan S, et al., Mather M. Multimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial. Scientific Data 10, 503 (2023). doi:10.1038/s41597-023-02396-5
Sources
Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.
- Yoo et al. 2023, Multimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial, Scientific Data paper
- participants.tsv of ds003823 snapshot 1.3.5 (CC0), counted per row computed
- File tree of ds003823 snapshot 1.3.5 (CC0), NIfTI files counted per subject, session and BIDS suffix computed