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CT MRI SPECT / nuclear medicine PET Brain

BIND

The Brain Imaging and Neurophysiology Database

Routine clinical brain MRI, CT, PET and SPECT from patients who had EEG or sleep studies, linked to their neurophysiology recordings and radiology reports for multimodal brain research. Converted to BIDS NIfTI, with LLM-extracted findings and automatic sequence labels.

Overview

BIND gathers the clinical brain imaging of patients who had an electroencephalogram (EEG) or a polysomnogram for clinical reasons over roughly 30 years at Mass General Brigham (Massachusetts General Hospital and Brigham and Women's Hospital) and Stanford. The images are linked by patient to EEG and sleep recordings released earlier on the Brain Data Science Platform, and to the de-identified radiology reports of each session. The authors built it for large neuroimaging studies, machine learning and research that combines imaging with neurophysiology.

Composition

The data descriptor reports 38,942 patients with 108,737 clinical encounters: 28,438 patients from Mass General Brigham and 10,504 from Stanford. Patients range from newborns to 106 years, covering healthy findings and a wide spread of neurological disease. Of 1,791,885 images, 1,723,699 are MRI, 54,137 CT, 5,093 PET and 526 SPECT. Race, death records, education and other demographics come with the data. The project page gives slightly different modality counts for release 1.0.

Acquisition

Scans were acquired in routine care, so protocols vary by indication and site. MRI was acquired at 1.5 T, 3 T and 7 T, mostly on Siemens and GE scanners. DICOM files were converted to NIfTI with dcm2niix and arranged in BIDS folders per site, patient and session, with JSON sidecars that keep scanner and acquisition details. Data were de-identified by the hospitals, date-shifted and screened with optical character recognition to remove burned-in text.

Annotations

MRI sequence types (T1, T2, FLAIR, diffusion, fMRI, SWI, perfusion, MR angiography) were assigned automatically from DICOM parameters with thresholds, Gaussian mixture clustering and keyword matching. On 100 hand-labeled sessions per site, accuracy was 0.9471 at Mass General Brigham and 0.8455 at Stanford. A biomedical Llama 3 model extracted findings from the reports and mapped them to 10 clinical categories with 150 subcategories; a neurologist checked 1,000 reports.

Known limitations

The report-derived findings are not curated by humans and may contain errors or hallucinations, so the full-text reports remain the reference. About 13% of diffusion scans lack b-values and b-vectors because de-identification overwrote those headers. Images are unprocessed and vary in quality and resolution. Sequence labels can be wrong, for example localizers labeled as T1 or T2, and neonatal scans are harder to classify. Access is limited to non-commercial research by credentialed users.

Cohort

Aggregate numbers from the sources below. Bars are relative to the 38,942 subjects.

Sex

  • Female 19,396 50%
  • Male 19,263 49%
  • Unknown 283 1%

Table 1 in Maschke et al. 2026, Scientific Data (BIND data descriptor)

Contrast / sequence

Scans

Groups can overlap

  • T1-weighted 438,159 24%
  • Diffusion-weighted 366,657 20%
  • MR angiography 196,802 11%
  • T2-weighted 166,390 9%
  • Susceptibility-weighted 165,751 9%
  • FLAIR 120,585 7%
  • BOLD fMRI 6,055 <1%

Table 3 in Maschke et al. 2026, Scientific Data (BIND data descriptor)

Field strength

Scans
  • 3 T 853,564 48%
  • 1.5 T 827,107 46%
  • 7 T 4,905 <1%

Table 2 in Maschke et al. 2026, Scientific Data (BIND data descriptor)

Age

mean 53.7 ± 23.2, up to 106

No age bins reported.

Demographics in BIND v1.0 project page on the Brain Data Science Platform; Demographics in Maschke et al. 2026, Scientific Data (BIND data descriptor)

Modality

Scans
  • MRI 1,723,699 96%
  • CT 54,137 3%
  • PET 5,093 <1%
  • SPECT / nuclear medicine 526 <1%

Table 2 in Maschke et al. 2026, Scientific Data (BIND data descriptor)

Scanner vendor

Scans
  • Siemens Healthineers 843,778 47%
  • GE HealthCare 808,340 45%

Imaging modalities and sequences in Maschke et al. 2026, Scientific Data (BIND data descriptor)

License and access

Our reading of the license, not legal advice. Before you use the data, read the original license and confirm that your use is allowed. We take no responsibility for how you use a dataset. Full disclaimer

Access
Credentialed

Identity check and ethics training (e.g. CITI) plus an agreement

BDSP credentialed account, CITI "Data or Specimens Only Research" training, a signed data use agreement and an AWS account ID. The paper states that commercial entities may get access through a separate institutional agreement with the participating hospitals.

Access page

BDSP Credentialed Health Data License 1.5.0

Non-commercial research license for credentialed users of the Brain Data Science Platform, who need human-subjects and HIPAA training and must sign the data use agreement. You must not share the data or record-level derivatives, try to identify people, or use the data for products or commercial AI models, and must release the code behind your publications.

Original license text Version read: 1.5.0, with the BDSP Credentialed Health Data Use Agreement (read 2026-10-11) Checked 2026-10-11

What you can do

  • No
  • No
  • Conditional
  • Conditional
  • Conditional

What you can share

  • No
  • No
  • Not stated

What you must do

  • Not stated
  • Share alike No
  • Yes
  • No
  • Manuscript review No
  • Yes
  • No
  • Conditional

Limits

  • Yes
  • Conditional

Commercial license: Conditional The BIND data descriptor states that commercial entities may get access through a separate institutional agreement with the participating hospitals; its terms are not published.

Citation

Maschke C, Hadar PN, Zhang Y, et al. The Brain Imaging and Neurophysiology Dataset of large-scale multimodal neural data. Sci Data 13, 1176 (2026). https://doi.org/10.1038/s41597-026-07421-x. Maschke C, Hadar P, Zhang Y, et al. The Brain Imaging and Neurophysiology Database (BIND) (version 1.0). Brain Data Science Platform (2025). https://doi.org/10.60508/mby8-3a26

Sources

Every number on this page comes from one of these documents. Each chart names the table or page it is taken from. The raw numbers are in stats.csv.